Every single time you have an immune response that is suboptimal in the presence of an infection, in the presence of a virus, that infected person, you are at risk for immune escape.
So that means that the virus can escape the immune response. And that is why I’m saying that these vaccines, I mean, in their own right, are, of course, excellent. But to use them in the midst of a pandemic and do mass vaccination, because then you provide within a very short period of time, the population with high antibody titers – so the virus comes under enormous pressure.
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I mean, that wouldn’t matter if you can eradicate a virus, if you can prevent infection, but these vaccines don’t prevent infection. . . . So if you think that by making new vaccines, a new vaccine against the new infectious strains, we going to catch up, it’s impossible to catch up. I mean, virus is not going to wait until we have those vaccines ready.
And as I was saying, the thing is, I mean, if you do this in the midst of a pandemic, that is an enormous problem. . . .These vaccines are excellent, but they are not made for administration to millions of people in the midst, in the heat of a pandemic.
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[The] [p]roblem is we induce a long lived antibody response. . . . Fact is that these long lived antibodies, which have high specificity, of course, for the virus. They out-compete our natural antibodies because they’re natural antibodies, they have a very broad spectrum, but they have low affinity. . . And so by doing this, even if your antibodies don’t work anymore, because there is resistance or, you know, that the strains are too different from the original strain, we still, these antibodies, specific antibodies will still continue to out-compete your natural antibodies. And that is a huge problem because I was saying just a few minutes ago, these natural antibodies, they provide you with broad protection.
This protection is, yes, it is variant nonspecific. Doesn’t matter what variant you get. It doesn’t even matter what type of coronavirus is coming in. They will protect you. Unless, of course, you suppress this level of innate immunity, or it is, for example, out-competed by long lived specific antibodies. . . .
Immunizing somebody is installing a new software on your computer. Don’t forget. I mean, these antibodies, they will be recalled every single time you’re encountering a coronavirus, right? I mean, you cannot just erase this. So this is very serious. This is very serious.
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I know there is reports on this, and there is a lot of serious thoughts about this. But I think what we are talking about right now, the epidemic or the pandemic problem of having a population that is at no point during the pandemic and to large extent, due to our intervention, has not a strong immune response. I mean, this is already serious enough. This is more concerning than one or the other adverse events that could maybe elicited, I’m not downplaying it, but that could maybe be elicited because people have antibodies that do no longer match very well with the strain they were or with the strain they are exposed to.
And therefore, you know, they build a complex, they don’t neutralize the virus, they build a complex and this complex could maybe even enhance viral entry into susceptible cells and hence lead to exacerbation of disease.
I mean, this may be possible, but the problem I’m talking about is a global problem. It’s not an individual getting an adverse event. It’s a global problem of, you know, making this virus increasingly infectious because we live it all the time, a chance and opportunity to escape an immune system and to drive this.
So to wake this up, you know, up to a level where the virus is so infectious, that we can even no longer control it, because I mean, these highly infectious strains, some people think, Oh, the virus is going to calm down and it will insert a number of mutations, you know, just to be gentle and kind with us. That’s not going to happen. I mean, this highly infectious range remains.
It is not going to be spontaneous mutations that all of a sudden would become, would make this virus again harmless because such a virus would have a competitive disadvantage, could not be dominant anymore, so that’s not going to happen. So we’re talking about a very, very, very serious problem here.
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It’s very clear what this is going to mean. . . . It is detrimental both on a population level, as on an individual level. And I’m telling you why. I think the population level I explained to you, we are increasingly facing highly infectious strains that already right now, we cannot control because basically what we are doing is that we are turning — when we vaccinate somebody, we are turning this person in a potential asymptomatic carrier that is shedding the virus.
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You are at the same time losing the most precious part of your immune system that you could ever imagine.
And that is your innate immune system, because the innate antibodies, the natural antibodies, the secretary IGMs will be out-competed by these antigen-specific antibodies for binding to the virus. And that will be long lived. That is a long lived suppression.
And you lose every protection against any viral variant or coronavirus variant, et cetera. So this means that you are left just with no single immune response with your, you know, it’s none, your immunity has become nil.
It’s all gone. The antibodies don’t work anymore. And your your innate immunity has been completely bypassed and this while highly infectious strains are circulating. . . . So, I mean, if that isn’t clear enough, I really don’t get it.
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. . . I’ve no criticism on the vaccines, but please use the right vaccine at the right place. And don’t use it in the heat of a pandemic on millions of millions of people.
We are going to pay a huge price for this. And I’m becoming emotional because I’m thinking of my children, of the younger generation. I mean, it’s just impossible what we are doing. We don’t understand the pandemic.
We have been turning it into an artificial pandemic. . . . What we are now doing is that we are really chasing this virus and it becomes all, you know, increasingly infectious. And I mean, this is just a situation that is completely, completely completely out of control.
So it’s also, we are now getting plenty of asymptomatic shedders. People who shed the virus because if they are vaccinated or they have even antibodies from previous disease, they can no longer control these highly infectious variants.
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