Have I mentioned in this thread that I now no longer recommend Vitamin D levels above 45ng/ml? The LEF misconstrued the research and the rest is history.
Cool story:
I'm not chasing youthfulness. I'm chasing health. People have been brainwashed to think that after you're 65, you're finished. We're told that old age is a continuous state of decline, and that we should stop working, slow down and prepare to die. I disagree. To me, a 65-year-old is young. I turn 92 this year. It is a frightening prospect – the law of averages is against me, and, yes, one day something will happen and that will be it. But until that day comes, I'm going to carry on working on my abs.
http://www.theguardian.com/lifeandstyle ... odybuilder
The Permanent Supplement Regime
Moderator: Global Moderator
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MachineGhost
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Re: The Permanent Supplement Regime
Last edited by MachineGhost on Thu Apr 24, 2014 10:25 am, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Mito Q and berberine
MG,
Apparently Mito Q is now commercially available (at least one place selling it for internal consumption). Thoughts?
Reub, I've read that berberine has laxative properties. Did you notice anything?
Apparently Mito Q is now commercially available (at least one place selling it for internal consumption). Thoughts?
Reub, I've read that berberine has laxative properties. Did you notice anything?
It was good being the party of Robin Hood. Until they morphed into the Sheriff of Nottingham
Re: The Permanent Supplement Regime
Luckily, I've not had any problems. I have lost 20 pounds though over the past 3 months, some of which must be attributable to the berberine. I went from 189 lbs. down to 169, going low carb, intermittent fasting (eating only between 11AM and 7PM), exercising in the morning either by running or playing some intense paddleball matches, and using berberine (400mgs 4X/day). My fasting blood sugar has come down from averaging about 105 to now averaging 97. I'd like to get it lower but it is stubborn! Prior to beginning this regimen, I was never able to lose even a pound! 
I can hardly wait for my next blood test to confirm my suspicions that my inflammation (CRP and homocysteine), and LDL cholesterol are down as well.
I can hardly wait for my next blood test to confirm my suspicions that my inflammation (CRP and homocysteine), and LDL cholesterol are down as well.
Last edited by Reub on Fri May 09, 2014 3:58 pm, edited 1 time in total.
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MachineGhost
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- Joined: Sat Nov 12, 2011 9:31 am
Re: Mito Q and berberine
I'm unconvinced. I want to see some comparison studies with ubiquinol/shilajit/biopqq before plunking down the increased cost.Benko wrote: Apparently Mito Q is now commercially available (at least one place selling it for internal consumption). Thoughts?
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
Got a promising new regime addition for you that is like a cholesterol/CRP/glucose reducer all-in-one: https://www.swansonvitamins.com/swanson ... 7-30-sgelsReub wrote: Luckily, I've not had any problems. I have lost 20 pounds though over the past 3 months, some of which must be attributable to the berberine. I went from 189 lbs. down to 169, going low carb, intermittent fasting (eating only between 11AM and 7PM), exercising in the morning either by running or playing some intense paddleball matches, and using berberine (400mgs 4X/day). My fasting blood sugar has come down from averaging about 105 to now averaging 97. I'd like to get it lower but it is stubborn! Prior to beginning this regimen, I was never able to lose even a pound!
I can hardly wait for my next blood test to confirm my suspicions that my inflammation (CRP and homocysteine), and LDL cholesterol are down as well.
I've tried Omega-7 from Seabuckthorn Oil before for the skin and didn't notice anything. My understanding is Omega-7 from seabuckthorn or macadamia has a lot of palmitic oil which negates the benefits of the pamitoleic, but this fish derived version is almost free of palmitic oil. Great complement to krill oil & fish oil.
I've been unknowingly undereating calories again, for the last 6 months. Grrrrrr! What a strange problem to have.
Last edited by MachineGhost on Sat May 31, 2014 3:38 pm, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
From Peruvian anchovies! Mmmmm!
Sounds like good stuff so I'm in for another $180 per year. I'm going to have to start selling used shoes on Ebay to support this habit.
Sounds like good stuff so I'm in for another $180 per year. I'm going to have to start selling used shoes on Ebay to support this habit.
Last edited by Reub on Thu May 15, 2014 5:45 pm, edited 1 time in total.
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MachineGhost
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Re: The Permanent Supplement Regime
Not bad. Taking both forms of Vitamin K together almost halves all cause mortality. The dose in K complexes are about twice the dose used in the study.
"Our results suggest that the dietary intake of both active forms of vitamin K has a potential protective role in cardiovascular mortality, cancer mortality, and all-cause mortality in a cohort of Mediterranean individuals at high cardiovascular disease risk with a relatively high consumption of this vitamin"
http://www.ncbi.nlm.nih.gov/pubmed/24647393
And some bad news:
Ingrid Caras from the California Institute for Regenerative Medicine spoke about how research endeavors in this discipline funded by taxpayers of California has led to an escalation in our understanding of molecular biology. She noted that the FDA approved clinical translational strategies are at least two decades from being instituted into western medicine.
Ught.
Here's an interesting abstract about Mark Mattson's presentation at the International Dose Response Society's recent conference:
“Compelling evidence from studies of rodents and humans suggest that intermittent fasting (IF), consisting of periodic (1-4 days per week) short (16-36 hours) fasts, can promote optimal health and can prevent and reverse disease processes in many chronic conditions including diabetes, cancers, cardiovascular disease and neurodegenerative brain disorders. In overweight human subjects, IF diets promote long-term weight loss with retention of lean mass, increased insulin sensitivity, and reduced inflammation and oxidative stress. Why, despite the fact that IF is a safe and effective intervention, do health care providers not prescribe IF diets to their patients? Regrettably, the reason for this lack of effort by the medical community is that no one profits from IF prescriptions. The processed food and agriculture industries would lose money if people ate less, and the pharmaceutical industry would ‘suffer’ if fewer people developed the diseases for which Pharma peddles their drugs. Medical training and practice is focused on technologically advanced treatments and specialists (cardiologists, neurologist, orthopedists, etc.) that it is not their job to tackle the underlying cause (which is often a couch potato lifestyle) of their patients’ diseases; instead, they have become drug-dispensing, scalpel-wielding robots. Medical school curricula are devoid of training on the profound health benefits of IF and exercise, and primary physicians often assume that patients will not comply with IF diets. In this presentation I will describe strategies for the implementation of IF diets in which patients are given a specific plan for the diet and for monitoring their progress. The physician and/or an assistant is in close communication with the patient via text messaging, social media, etc. with the purpose of guiding them through the 1 – 2 month period that is often required for a person to adjust to the IF eating pattern.”?
"Our results suggest that the dietary intake of both active forms of vitamin K has a potential protective role in cardiovascular mortality, cancer mortality, and all-cause mortality in a cohort of Mediterranean individuals at high cardiovascular disease risk with a relatively high consumption of this vitamin"
http://www.ncbi.nlm.nih.gov/pubmed/24647393
And some bad news:
Ingrid Caras from the California Institute for Regenerative Medicine spoke about how research endeavors in this discipline funded by taxpayers of California has led to an escalation in our understanding of molecular biology. She noted that the FDA approved clinical translational strategies are at least two decades from being instituted into western medicine.
Ught.
Here's an interesting abstract about Mark Mattson's presentation at the International Dose Response Society's recent conference:
“Compelling evidence from studies of rodents and humans suggest that intermittent fasting (IF), consisting of periodic (1-4 days per week) short (16-36 hours) fasts, can promote optimal health and can prevent and reverse disease processes in many chronic conditions including diabetes, cancers, cardiovascular disease and neurodegenerative brain disorders. In overweight human subjects, IF diets promote long-term weight loss with retention of lean mass, increased insulin sensitivity, and reduced inflammation and oxidative stress. Why, despite the fact that IF is a safe and effective intervention, do health care providers not prescribe IF diets to their patients? Regrettably, the reason for this lack of effort by the medical community is that no one profits from IF prescriptions. The processed food and agriculture industries would lose money if people ate less, and the pharmaceutical industry would ‘suffer’ if fewer people developed the diseases for which Pharma peddles their drugs. Medical training and practice is focused on technologically advanced treatments and specialists (cardiologists, neurologist, orthopedists, etc.) that it is not their job to tackle the underlying cause (which is often a couch potato lifestyle) of their patients’ diseases; instead, they have become drug-dispensing, scalpel-wielding robots. Medical school curricula are devoid of training on the profound health benefits of IF and exercise, and primary physicians often assume that patients will not comply with IF diets. In this presentation I will describe strategies for the implementation of IF diets in which patients are given a specific plan for the diet and for monitoring their progress. The physician and/or an assistant is in close communication with the patient via text messaging, social media, etc. with the purpose of guiding them through the 1 – 2 month period that is often required for a person to adjust to the IF eating pattern.”?
Last edited by MachineGhost on Wed May 21, 2014 7:44 am, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
-
MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
I've been asked over the years what my personal regime is. As I've just finished my annual upgrading review, I've pasted it below. The format is the seller to buy it from, the product name, the size of the individual capsule (or package size if food/powder) and then the number of capsules taken/serving size. If there's no formal brand name in the product name, then it is the in-house brand of the seller. Normally, I will only choose a non in-house brand if a branded product is best of breed or doesn't contain a filler ingredient I disagree with. I prefer to give the edge to VitaCost due to the 8% cash back via BeFrugal, unless Swanson is substantially lower or has a better formulation.
A disconcerting change I made this past year was to dump all carotenoids and xanthophylls in favor of a higher dose of astaxanthin. The carotenoids seem to oxidize cell membranes, whereas astaxanthin integrates and stabilizes them. I've also upgraded the curcumin to a superior version that does not require conversion by the body of curcuminoids into the active endproducts. And I switched from GliSODin which contains a gut-damaging gluten carrier to a sublingual S.O.D. which I'm still not sure is as effective or better. I can only judge that by if there's tiredness/fatique when switching from one version to the other. I also recently lowered the apple fiber and unmodified potato starch dose as I'm concerned with them absorbing the fat soluble supplements and wasting money; I may move both to just taking at bedtime. I also added strontium for bone biogenesis and BioPQQ for mitochondrial biogensis, as well as fish Omega-7 to round out the fish oil and krill oil. I also dumped N-Acetyl Cysteine (NAC) as it was causing me pain in my floating rib and went with reduced glutathione. I'm not convinced reduced gluthathione works as good as NAC even though the bioavailability of glutathione has been recently proven.
Wakeup:
VitaCost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Acetyl L-Carnitine (500mg) [1]
Swanson Triple Strength R-Fraction Alpha Lipoic Acid (300mg) [1]
Amazon Premier S.O.D. (1210u) [1]
Swanson Pterostilbene (50mg) [1]
VitaCost Doctor's Best Fisetin (100mg) [1]
Swanson Advanced Tetrahydro-Curcuminoids 95% (200mg) [1]
PureFormulas Iodoral (12.5) [1/4]
Swanson Activated B-Complex High Bioavailability [1]
VitaCost Source Naturals DMAE (130mg) [1]
Swanson Ecklonia Cava Extract (53mg) [1]
VitaCost Healthy Origins Setria L-Glutathione (500mg) [1]
Amazon Natural Radiance Topical DHEA Cream (2oz) [2 pumps]
Breakfast:
Local Frozen Blackberries (16oz) [1/2C]
iHerb NOW Apple Fiber Powder (12oz) [1T]
VitaCost Bob's Red Mill Unmodified Potato Starch (24oz) [1T]
VitaCost KAL Pure Stevia Extract Powder (3.5oz) [1]
Swanson Lecithin Granules Non-GMO (3lbs) [1T]
TrueNutrition Beef Protein Isolate (64oz) [90 cc]
Honeyville Dextrose Powder (50lb) [1/4C + 1T]
Local Napa Valley Naturals Extra Virgin Olive Oil (25.7oz) [2T]
Swanson Provinal Purified Omega-7 (210mg) [1]
Swanson NOW Tri-3D Omega (1g) [3]
VitaCost Superior Krill Oil (500mg) [1]
VitaCost Vitamin D3 (5000 IU) [1]
VitaCost Ultra Vitamin K with Advanced K2 Complex [1]
VitaCost LEF Super Ubiquinol CoQ10 with Shilajit (50mg) [1]
VitaCost Jarrow PQQ (10mg) [1]
VitaCost Nutrex BioAstin Supreme Astaxanthin (6mg) [1]
Swanson Healthy Origins Tocomin SupraBio (50mg) [1]
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson Advanced Research Lithium Orotate (4.6mg) [1/2]
Swanson Niacin-Bound Chromium (200mcg) [1]
VitaCost Source Naturals Copper Sebacate (3mg) [1]
VitaCost Olympian Labs DIM (100mg) [1]
Amazon Prescript-Assist [Weekly]
Lunch:
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson NOW Chlorophyll (100mcg) [1]
Swanson Healthy Origins SelenoExcell Selenium (200mcg) [1]
Swanson Niacin-Bound Chromium (200mcg) [1]
Swanson Vitamin D & Boron Complex (6mg) [1]
VitaCost Source Naturals OptiZinc (30mg) [1]
Dinner:
VitaCost Albion Chelated Magnesium (200mg) [2]
Bedtime:
VitaCost VitaCost Melatonin Liquid (1/2 dropper) [1]
VitaCost Vitacost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Nature's Herbs Nettle Root-Power (300mg) [1]
VitaCost Vitacost Strontium (340mg) [2]
Workout:
Honeyville Dextrose Powder (50lb) [2.75T]
Tnation Leucine Structured Peptides (300g) [2 scoops]
Honeyville Dextrose Powder (50lb) [5.33T]
Swanson CreaPure Creatine Powder (1kg) [1 scoop]
TrueNutrition Beef Protein Isolate (64oz) [45 cc]
I've excluded bioagents in protocols I'm experimenting with, which is only four or five things. Due to copy and paste issues, I can't include the rational for each item from my spreadsheet.
A disconcerting change I made this past year was to dump all carotenoids and xanthophylls in favor of a higher dose of astaxanthin. The carotenoids seem to oxidize cell membranes, whereas astaxanthin integrates and stabilizes them. I've also upgraded the curcumin to a superior version that does not require conversion by the body of curcuminoids into the active endproducts. And I switched from GliSODin which contains a gut-damaging gluten carrier to a sublingual S.O.D. which I'm still not sure is as effective or better. I can only judge that by if there's tiredness/fatique when switching from one version to the other. I also recently lowered the apple fiber and unmodified potato starch dose as I'm concerned with them absorbing the fat soluble supplements and wasting money; I may move both to just taking at bedtime. I also added strontium for bone biogenesis and BioPQQ for mitochondrial biogensis, as well as fish Omega-7 to round out the fish oil and krill oil. I also dumped N-Acetyl Cysteine (NAC) as it was causing me pain in my floating rib and went with reduced glutathione. I'm not convinced reduced gluthathione works as good as NAC even though the bioavailability of glutathione has been recently proven.
Wakeup:
VitaCost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Acetyl L-Carnitine (500mg) [1]
Swanson Triple Strength R-Fraction Alpha Lipoic Acid (300mg) [1]
Amazon Premier S.O.D. (1210u) [1]
Swanson Pterostilbene (50mg) [1]
VitaCost Doctor's Best Fisetin (100mg) [1]
Swanson Advanced Tetrahydro-Curcuminoids 95% (200mg) [1]
PureFormulas Iodoral (12.5) [1/4]
Swanson Activated B-Complex High Bioavailability [1]
VitaCost Source Naturals DMAE (130mg) [1]
Swanson Ecklonia Cava Extract (53mg) [1]
VitaCost Healthy Origins Setria L-Glutathione (500mg) [1]
Amazon Natural Radiance Topical DHEA Cream (2oz) [2 pumps]
Breakfast:
Local Frozen Blackberries (16oz) [1/2C]
iHerb NOW Apple Fiber Powder (12oz) [1T]
VitaCost Bob's Red Mill Unmodified Potato Starch (24oz) [1T]
VitaCost KAL Pure Stevia Extract Powder (3.5oz) [1]
Swanson Lecithin Granules Non-GMO (3lbs) [1T]
TrueNutrition Beef Protein Isolate (64oz) [90 cc]
Honeyville Dextrose Powder (50lb) [1/4C + 1T]
Local Napa Valley Naturals Extra Virgin Olive Oil (25.7oz) [2T]
Swanson Provinal Purified Omega-7 (210mg) [1]
Swanson NOW Tri-3D Omega (1g) [3]
VitaCost Superior Krill Oil (500mg) [1]
VitaCost Vitamin D3 (5000 IU) [1]
VitaCost Ultra Vitamin K with Advanced K2 Complex [1]
VitaCost LEF Super Ubiquinol CoQ10 with Shilajit (50mg) [1]
VitaCost Jarrow PQQ (10mg) [1]
VitaCost Nutrex BioAstin Supreme Astaxanthin (6mg) [1]
Swanson Healthy Origins Tocomin SupraBio (50mg) [1]
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson Advanced Research Lithium Orotate (4.6mg) [1/2]
Swanson Niacin-Bound Chromium (200mcg) [1]
VitaCost Source Naturals Copper Sebacate (3mg) [1]
VitaCost Olympian Labs DIM (100mg) [1]
Amazon Prescript-Assist [Weekly]
Lunch:
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson NOW Chlorophyll (100mcg) [1]
Swanson Healthy Origins SelenoExcell Selenium (200mcg) [1]
Swanson Niacin-Bound Chromium (200mcg) [1]
Swanson Vitamin D & Boron Complex (6mg) [1]
VitaCost Source Naturals OptiZinc (30mg) [1]
Dinner:
VitaCost Albion Chelated Magnesium (200mg) [2]
Bedtime:
VitaCost VitaCost Melatonin Liquid (1/2 dropper) [1]
VitaCost Vitacost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Nature's Herbs Nettle Root-Power (300mg) [1]
VitaCost Vitacost Strontium (340mg) [2]
Workout:
Honeyville Dextrose Powder (50lb) [2.75T]
Tnation Leucine Structured Peptides (300g) [2 scoops]
Honeyville Dextrose Powder (50lb) [5.33T]
Swanson CreaPure Creatine Powder (1kg) [1 scoop]
TrueNutrition Beef Protein Isolate (64oz) [45 cc]
I've excluded bioagents in protocols I'm experimenting with, which is only four or five things. Due to copy and paste issues, I can't include the rational for each item from my spreadsheet.
Last edited by MachineGhost on Sat May 31, 2014 3:48 pm, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
Thanks for posting.
DMAE I've heard mixed things about. What made you decide to take it?
FYI: there are liposomal formulations of glutathione.
DMAE I've heard mixed things about. What made you decide to take it?
FYI: there are liposomal formulations of glutathione.
It was good being the party of Robin Hood. Until they morphed into the Sheriff of Nottingham
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
DMAE for reducing lipofuscion (age spots) deposits. It also works with the lecithin to generate acetylcholine. Before I discovered lecithin to combat brain fog, I took a trinity of DMAE, Huperzine-A and CDP-Choline to keep it at bay.Benko wrote: Thanks for posting.
DMAE I've heard mixed things about. What made you decide to take it?
FYI: there are liposomal formulations of glutathione.
I know about liposomal glutathione but it's simply too expensive to buy. I've been thinking about trying alternate day dosing with NAC and glutathione to see if that makes the NAC tolerable. I'm also waiting to see the results of experiments with various homemade liposomal supplements to see if it's even worth going down that path myself.
Oh yeah, I also dropped all the anti-allergy supplements... quercetin, luteolin, and the various others I've tried.
I should mention I will be phasing out the individual mineral supplements during the rest of the year and just going to a single multi-mineral supplement (which is proving hard to find that isn't junx). It turns out that hair elements analysis is not an accurate indication of mineral defenciencies in the rest of the body, so anything for an excuse to reduce the number of supplements!
Last edited by MachineGhost on Sat May 31, 2014 11:52 am, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
Thank you for the list, MG! What are the possible effects on the liver and/or kidneys in consuming all of these?
-
MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
None that I'm aware of. Toxins are typically found in the plant matter matrix, so herbs require more awareness of negative interactions.Reub wrote: Thank you for the list, MG! What are the possible effects on the liver and/or kidneys in consuming all of these?
Last edited by MachineGhost on Sun Jun 01, 2014 6:36 am, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
MG, can you explain the Nutrex BioAstin Supreme Astaxanthin (6mg) supplement please?MachineGhost wrote: I've been asked over the years what my personal regime is. As I've just finished my annual upgrading review, I've pasted it below. The format is the seller to buy it from, the product name, the size of the individual capsule (or package size if food/powder) and then the number of capsules taken/serving size. If there's no formal brand name in the product name, then it is the in-house brand of the seller. Normally, I will only choose a non in-house brand if a branded product is best of breed or doesn't contain a filler ingredient I disagree with. I prefer to give the edge to VitaCost due to the 8% cash back via BeFrugal, unless Swanson is substantially lower or has a better formulation.
A disconcerting change I made this past year was to dump all carotenoids and xanthophylls in favor of a higher dose of astaxanthin. The carotenoids seem to oxidize cell membranes, whereas astaxanthin integrates and stabilizes them. I've also upgraded the curcumin to a superior version that does not require conversion by the body of curcuminoids into the active endproducts. And I switched from GliSODin which contains a gut-damaging gluten carrier to a sublingual S.O.D. which I'm still not sure is as effective or better. I can only judge that by if there's tiredness/fatique when switching from one version to the other. I also recently lowered the apple fiber and unmodified potato starch dose as I'm concerned with them absorbing the fat soluble supplements and wasting money; I may move both to just taking at bedtime. I also added strontium for bone biogenesis and BioPQQ for mitochondrial biogensis, as well as fish Omega-7 to round out the fish oil and krill oil. I also dumped N-Acetyl Cysteine (NAC) as it was causing me pain in my floating rib and went with reduced glutathione. I'm not convinced reduced gluthathione works as good as NAC even though the bioavailability of glutathione has been recently proven.
Wakeup:
VitaCost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Acetyl L-Carnitine (500mg) [1]
Swanson Triple Strength R-Fraction Alpha Lipoic Acid (300mg) [1]
Amazon Premier S.O.D. (1210u) [1]
Swanson Pterostilbene (50mg) [1]
VitaCost Doctor's Best Fisetin (100mg) [1]
Swanson Advanced Tetrahydro-Curcuminoids 95% (200mg) [1]
PureFormulas Iodoral (12.5) [1/4]
Swanson Activated B-Complex High Bioavailability [1]
VitaCost Source Naturals DMAE (130mg) [1]
Swanson Ecklonia Cava Extract (53mg) [1]
VitaCost Healthy Origins Setria L-Glutathione (500mg) [1]
Amazon Natural Radiance Topical DHEA Cream (2oz) [2 pumps]
Breakfast:
Local Frozen Blackberries (16oz) [1/2C]
iHerb NOW Apple Fiber Powder (12oz) [1T]
VitaCost Bob's Red Mill Unmodified Potato Starch (24oz) [1T]
VitaCost KAL Pure Stevia Extract Powder (3.5oz) [1]
Swanson Lecithin Granules Non-GMO (3lbs) [1T]
TrueNutrition Beef Protein Isolate (64oz) [90 cc]
Honeyville Dextrose Powder (50lb) [1/4C + 1T]
Local Napa Valley Naturals Extra Virgin Olive Oil (25.7oz) [2T]
Swanson Provinal Purified Omega-7 (210mg) [1]
Swanson NOW Tri-3D Omega (1g) [3]
VitaCost Superior Krill Oil (500mg) [1]
VitaCost Vitamin D3 (5000 IU) [1]
VitaCost Ultra Vitamin K with Advanced K2 Complex [1]
VitaCost LEF Super Ubiquinol CoQ10 with Shilajit (50mg) [1]
VitaCost Jarrow PQQ (10mg) [1]
VitaCost Nutrex BioAstin Supreme Astaxanthin (6mg) [1]
Swanson Healthy Origins Tocomin SupraBio (50mg) [1]
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson Advanced Research Lithium Orotate (4.6mg) [1/2]
Swanson Niacin-Bound Chromium (200mcg) [1]
VitaCost Source Naturals Copper Sebacate (3mg) [1]
VitaCost Olympian Labs DIM (100mg) [1]
Amazon Prescript-Assist [Weekly]
Lunch:
VitaCost Nature's Way Calcium Citrate/Carbonate/Malate (250mg) [2]
Swanson NOW Chlorophyll (100mcg) [1]
Swanson Healthy Origins SelenoExcell Selenium (200mcg) [1]
Swanson Niacin-Bound Chromium (200mcg) [1]
Swanson Vitamin D & Boron Complex (6mg) [1]
VitaCost Source Naturals OptiZinc (30mg) [1]
Dinner:
VitaCost Albion Chelated Magnesium (200mg) [2]
Bedtime:
VitaCost VitaCost Melatonin Liquid (1/2 dropper) [1]
VitaCost Vitacost L-Carnosine (500mg) [1]
VitaCost Solaray Two Stage Time Release Vitamin C (1000mg) [1]
VitaCost Nature's Herbs Nettle Root-Power (300mg) [1]
VitaCost Vitacost Strontium (340mg) [2]
Workout:
Honeyville Dextrose Powder (50lb) [2.75T]
Tnation Leucine Structured Peptides (300g) [2 scoops]
Honeyville Dextrose Powder (50lb) [5.33T]
Swanson CreaPure Creatine Powder (1kg) [1 scoop]
TrueNutrition Beef Protein Isolate (64oz) [45 cc]
I've excluded bioagents in protocols I'm experimenting with, which is only four or five things. Due to copy and paste issues, I can't include the rational for each item from my spreadsheet.
Also, is there anything on this list with specific use for inflammation (CRP and homocysteine issues) and/or glucose metabolism?
Also, I've read that DHEA is well below optimum for most men after age 30 and can be particularly effective for reducing fasting blood glucose and metabilic syndrome. Any thoughts on its use? Thanks!
Last edited by Reub on Sun Jun 01, 2014 9:31 pm, edited 1 time in total.
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MachineGhost
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Re: The Permanent Supplement Regime
I don't know and it's an ongoing concern, but since production of endogenous antioxidants drop as you age, that's a good enough reason to bring it back into the theoretical hormetic balance.Benko wrote: 1. How do you know that your supplementation of glutathione precursors does not put you "over the hump" and too far to the right on the inverted U shaped curve for amount of glutathione?
I take bioavailable glutathione and SOD; catalase is not bioavailable AFAIK but it could be a situation as with glutathione where the question wasn't really tested experimentally. Bioavailable SOD does contains a little catalase when it is derived from melons. I don't know if there is a connection, but I noticed grey hairs that started during the time frame I switched over from GliSODin to Premier SOD. As catalase plays a role in preventing the hydrogen peroxide oxidiation of hair, it's a possible sign that I may be better off with GliSODin, despite the gluten. Unfortunately, I bought a year's supply of Premier SOD at a great discount, so I'm stuck with it for another half year.Benko wrote:2. Endogenous antioxidants include not just glutathione, but catalase, SOD and perhaps one or two I'm forgetting. If you are willing to share, are you taking precursors of these as well? You can paste this question/your answer into the supplement thread if you think more appropriate.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
Astaxanthin is a member of the carotenoids family and is derived from algae (its what gives salmon, shrimp and flamingos their pink color) since algae has to defend itself from constant ultraviolent radiation from the sun near the surface of the sea. Its specialty is in preventing sunburn as well as eye diseases, especially the inner eye oxidization from being a constant PC user. Unlike the other members of the carotenoid family, it does not oxidize cell membranes, but actually integrates into the lipid bilayer vertically and stabilizes it from oxidization. I believe that as long as you eat enough colorful vegetables, you will get a passable amount of carotenoids, but taking the oxidization potential of concentrated carotenoid supplements into consideration, I choosed to err on the side of caution. I did this with some regrets because I know carotenoids are woefully indequate in the food supply compared to supplements. Anyway, I've never noticed a dramatic change in my vision from starting or dropping carotenoids, but it is very noticeable when starting or stopping astaxanthin and lasts for about a week (astaxanthin builds up in the body). In the first season of Dirty Jobs, Mike goes to work in episode 15 at an astaxanthin processing plant in Hawaii.Reub wrote: MG, can you explain the Nutrex BioAstin Supreme Astaxanthin (6mg) supplement please?
Also, is there anything on this list with specific use for inflammation (CRP and homocysteine issues) and/or glucose metabolism?
Also, I've read that DHEA is well below optimum for most men after age 30 and can be particularly effective for reducing fasting blood glucose and metabilic syndrome. Any thoughts on its use? Thanks!
I've pretty much told you all about them already: ALA, curcumin, pre-activated B's (benfotiamine, P5P), pterostilbene, unmodified potato starch, chromium, etc..Also, is there anything on this list with specific use for inflammation (CRP and homocysteine issues) and/or glucose metabolism?
I wouldn't lump DHEA into doing that specifically, but more because restoring your age-onset hormonal imbalance fixes metabolic disorder, Syndrome X, high cholesterol, fat induced estrogen imbalance, etc.. DHEA will lower cortisol as well as being converted into testosterone when applied properly. So one or the other maybe. I've not been too impressed in my experiments with testosterone boosting herbs.Also, I've read that DHEA is well below optimum for most men after age 30 and can be particularly effective for reducing fasting blood glucose and metabilic syndrome. Any thoughts on its use? Thanks!
Last edited by MachineGhost on Mon Jun 02, 2014 6:47 am, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
Reub,
I would think you know all this, but in case not
Lowering CRP:
--lose weight if overweight
--VIt C
--Fish oil
--GLA e.g. borage oil
--Curcumin
--soluable fiber
--dark chocolate
--ginger
there are others e.g. more complete list here:
http://www.lef.org/magazine/mag2009/may ... cks_01.htm
I would think you know all this, but in case not
Lowering CRP:
--lose weight if overweight
--VIt C
--Fish oil
--GLA e.g. borage oil
--Curcumin
--soluable fiber
--dark chocolate
--ginger
there are others e.g. more complete list here:
http://www.lef.org/magazine/mag2009/may ... cks_01.htm
It was good being the party of Robin Hood. Until they morphed into the Sheriff of Nottingham
Re: The Permanent Supplement Regime
Yes, Benko, I do know much of this but I am always wanting to learn more. Thank you!Benko wrote: Reub,
I would think you know all this, but in case not
Lowering CRP:
--lose weight if overweight
--VIt C
--Fish oil
--GLA e.g. borage oil
--Curcumin
--soluable fiber
--dark chocolate
--ginger
there are others e.g. more complete list here:
http://www.lef.org/magazine/mag2009/may ... cks_01.htm
I take all of those on your list except for the borage oil and the ginger. However, I take a few others such as 5-loxin, mixed Vitamin K, Omega 7's, green tea and blueberry extracts, black and white tea in drinking form, to name a few.
I have lost 22 pounds (mostly around the mid-section) over the past 4 months and now weigh in at a svelte 167 lbs. (5'11''). I attribute some of this to using berberine and chromium, along with changing to a very low carb diet and employing intermittent fasting (usually eating only between 11AM and 7PM) along with daily hearty exercise. I just got back from having my teeth cleaned at the dentist office so this should help my CRP too. I am due for a blood test soon and will share my results.
I was really most curious about the DHEA more than anything else...I mean how wonderful would it be to have your sex hormones restored to youthful levels, reduce or eliminate metabolic syndrome, reduce inflammation, and lower fasting blood glucose levels? Has it been shown to really do all of these things? What are the drawbacks?
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MachineGhost
- Executive Member
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- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
DHEA does have some positive health effects but I believe they are probably from being converted into testosterone which is the real powerhouse hormone in restoring health (along with HGH), so logically if you wanted maximum effect then doing testosterone straight up could be ideal. I don't advocate doing that yet because I've found there to be a serious lack of concern over dosing, complications, side effects and other hormone imbalances and doctors in general are woefully ignorant (and prejudiced) of just about anything on the subject. It's not helped by those complicit doctors acting as drug pushers and prescribing testosterone to any patient that asks or is willing to pay all just because they saw a TV commercial for it. So I will continue to study the topic until I am convinced all the nooks and crannies have been peered into by my brain.Reub wrote: I was really most curious about the DHEA more than anything else...I mean how wonderful would it be to have your sex hormones restored to youthful levels, reduce or eliminate metabolic syndrome, reduce inflammation, and lower fasting blood glucose levels? Has it been shown to really do all of these things? What are the drawbacks?
DHEA was really big back in the 90's when it first burst onto the scene, but the hype has long ago died down even though the science hasn't gone away. It's taken me over a decade to finally learn how to take the damn thing correctly... and I mean quite recently! That's one thing FDA mandated Phase II drug trials have going for itself: to determine the best dosage form and quantity.
I believe DHEA doesn't have a negative feedback mechanism as with the other hormones or T boosting herbs. What's to worry about is taking it orally which is a big no no for any hormone. I'm one of those people that get heart palpitations from taking DHEA orally (micronized or not) or even sublingually, even on tiny 5 mg doses. If you want to try it out, just make sure you get your DHEA and estradiol blood levels tested 30-days after starting and adjust your regime if necessary. This is the least complex and safest level you can operate at when dealing with hormones. Only melatonin is simpler.
Last edited by MachineGhost on Mon Jun 02, 2014 6:58 pm, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
Thanks again for the wonderful service that you provide! And that goes for Benko and WiseOne as well! We are all lucky to have you here.
So MG what is the proper way to take the DHEA? Do you recommend starting at 5mgs? My fasting blood sugar is hovering around 106 most days and I'd like this to help. I've read that this will effect insulin in a positive way. If this is not successful then metformin might be next.
So MG what is the proper way to take the DHEA? Do you recommend starting at 5mgs? My fasting blood sugar is hovering around 106 most days and I'd like this to help. I've read that this will effect insulin in a positive way. If this is not successful then metformin might be next.
Re: The Permanent Supplement Regime
Reub,
Well while I went to dinner and was composing my reply MG beat me to it.
The problem with DHEA is that is can be converted to the testosterone or estrogen pathway:
http://www.elsevierimages.com/image/28518.htm
If you want to take DHEA my personal preference is sublingual (LEF sells sublingual). I vaguely remember it has something to do with the liver i.e. any oral ingested DHEA goes through the liver whereas SL does not. And like MG says get bloodwork before and after.
There is also 7-keto you might look into (never learned much about that).
I am way too conservative to ever do HGH (and there are controversies regarding that), though taking like 1/4 the standard anti-aging dose might be more reasonable.
Berberine is more effective than metformin, so why add that?
Well while I went to dinner and was composing my reply MG beat me to it.
The problem with DHEA is that is can be converted to the testosterone or estrogen pathway:
http://www.elsevierimages.com/image/28518.htm
If you want to take DHEA my personal preference is sublingual (LEF sells sublingual). I vaguely remember it has something to do with the liver i.e. any oral ingested DHEA goes through the liver whereas SL does not. And like MG says get bloodwork before and after.
There is also 7-keto you might look into (never learned much about that).
I am way too conservative to ever do HGH (and there are controversies regarding that), though taking like 1/4 the standard anti-aging dose might be more reasonable.
Berberine is more effective than metformin, so why add that?
It was good being the party of Robin Hood. Until they morphed into the Sheriff of Nottingham
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
There is now an effective HMB metabolite of leucine which is a component of the branch chained amino acids (BCAA) which is highest in whey protein. See the evolution? Gotta love science+capitalism! http://www.muscletech.com/products/clear-muscle/
A bit pricey and I doubt it would work well taking it just on workout days. I'll try it when I'm done with the leucine peptides.
Reub, I answered you privately about the optimal DHEA form and application and aromatization issues you need to be aware of.
Benko, the HGH "controversy" is overrated and lives on lack of science, politics and urban legends. The health problems were coming from abusers and/or idiotic doctors dosing past physiological levels which is fvcking stupid with anything, but especially hormones. Anyway, HGH is extremely short-lived and is converted into IGF-1 via the liver which is the active metabolite (the body pulses HGH at around 2am I think), so taking a natural IGF-1 source from deer antler velvet is essentially the same thing. There's also a HGH-releasing amino acid supplement for the pituitary (or hypothalamus?) that doesn't incur a negative feedback loop like sermotrophin (sp?), but it currently costs $199 per month. Just like low T, it seems that having low IGF-1 is indicative for cancer, not IGF-1 per se, though there's certainly many studies showing IGF-1 is correlated with cancer or whatever negative outcome they're looking for, so I feel IGF-1 is worth more caution until there's better clarification of correlation vs causation. Probably a moot point if you take the appropriate supplements to shut down cancerific oncogenes and epigenetics, but thats very uncommon common sense with people that inject HGH or do other "high level" extreme only stuff (there's a guy online somewhere that's been injecting insulin for "anti-aging purposes" for about two decades and hes not even diabetic!).
An issue with hormones is in dosing them pulsatile style to mimick nature, not flooding the body with free forms all at once which is unnatural.
A bit pricey and I doubt it would work well taking it just on workout days. I'll try it when I'm done with the leucine peptides.
Reub, I answered you privately about the optimal DHEA form and application and aromatization issues you need to be aware of.
Benko, the HGH "controversy" is overrated and lives on lack of science, politics and urban legends. The health problems were coming from abusers and/or idiotic doctors dosing past physiological levels which is fvcking stupid with anything, but especially hormones. Anyway, HGH is extremely short-lived and is converted into IGF-1 via the liver which is the active metabolite (the body pulses HGH at around 2am I think), so taking a natural IGF-1 source from deer antler velvet is essentially the same thing. There's also a HGH-releasing amino acid supplement for the pituitary (or hypothalamus?) that doesn't incur a negative feedback loop like sermotrophin (sp?), but it currently costs $199 per month. Just like low T, it seems that having low IGF-1 is indicative for cancer, not IGF-1 per se, though there's certainly many studies showing IGF-1 is correlated with cancer or whatever negative outcome they're looking for, so I feel IGF-1 is worth more caution until there's better clarification of correlation vs causation. Probably a moot point if you take the appropriate supplements to shut down cancerific oncogenes and epigenetics, but thats very uncommon common sense with people that inject HGH or do other "high level" extreme only stuff (there's a guy online somewhere that's been injecting insulin for "anti-aging purposes" for about two decades and hes not even diabetic!).
An issue with hormones is in dosing them pulsatile style to mimick nature, not flooding the body with free forms all at once which is unnatural.
Last edited by MachineGhost on Thu Jun 05, 2014 6:41 pm, edited 1 time in total.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
I forgot to add straight-up Glucosamine KCl to my regime list. I get it free every quarter via an OTC credit from my health insurance plan. While I take it for joints and it doesn't really seem to do anything for that per se in me (I feel a combo glucosamine/chondroitin/MSM formula at the proper doses is better), there are new anti-aging benefits being discovered with it.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Re: The Permanent Supplement Regime
Examine.com is now offering supplement stack guides on specific health targets. Paul Jamimet seems to be endorsing their purchase here: http://perfecthealthdiet.com/2014/06/ex ... ck-guides/
The stacks can be purchased individually or in their entirety here: http://store.examine.com/store/stack-guides/
All of the stack guides can be purchased as a bundled book for $119 or separately for as low as $35.
The stacks can be purchased individually or in their entirety here: http://store.examine.com/store/stack-guides/
All of the stack guides can be purchased as a bundled book for $119 or separately for as low as $35.
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MachineGhost
- Executive Member
- Posts: 10054
- Joined: Sat Nov 12, 2011 9:31 am
Re: The Permanent Supplement Regime
I bought all the guides when it was available at the discounted bundle price, but I've only read the weight loss one so far. I think the main advantage is more in the free lifetime updates because frankly they don't offer a lot in the way of interesting ideas due to their idea of a lack of convincing evidence. They want human trials only which is a tough and expensive standard for supplements.Reub wrote: Examine.com is now offering supplement stack guides on specific health targets. Paul Jamimet seems to be endorsing their purchase here: http://perfecthealthdiet.com/2014/06/ex ... ck-guides/
The stacks can be purchased individually or in their entirety here: http://store.examine.com/store/stack-guides/
All of the stack guides can be purchased as a bundled book for $119 or separately for as low as $35.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!
Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet. I should not be considered as legally permitted to render such advice!